#adversarial-fine-tuning News & Analysis

Single-Cell Cross-Modal Transfer by Adversarial Fine-Tuning of Foundation Models

Researchers propose a foundation model approach using adversarial fine-tuning to translate between unpaired spatial transcriptomics and single-cell RNA sequencing data. The method addresses the scarcity of paired datasets by leveraging the abundance of individual modalities, outperforming existing multi-omics translation approaches.