AINeutralarXiv – CS AI · 10h ago6/10
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Bridging Sequence and Graph Structure for Epigenetic Age Prediction
Researchers present a novel machine learning framework that combines DNA sequence analysis with graph neural networks to predict biological age from methylation patterns, achieving 12.8% improvement over existing methods. The approach uses handcrafted sequence features rather than deep learning to encode biological context, demonstrating practical advantages in aging research applications.