AIBullisharXiv – CS AI · 6h ago7/10
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OmegAMP: Targeted AMP Discovery via Biologically Informed Generation
OmegAMP is a deep learning framework that uses diffusion-based generation with biologically informed encoding to design antimicrobial peptides (AMPs) with unprecedented controllability and precision. In wet lab validation, 24 of 25 candidate peptides (96%) demonstrated antimicrobial activity, including against multi-drug resistant strains, potentially accelerating drug discovery for antibiotic-resistant infections.