AINeutralarXiv – CS AI · 10h ago6/10
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Shapley Regression for Rare Disease Diagnosis Support: a case study on APDS
Researchers propose Shapley regression, a game-theoretic machine learning method for diagnosing APDS, a rare genetic immune disorder. The approach combines interpretability with predictive power by modeling symptom interactions while maintaining transparency, validated on both public datasets and a real-world cohort of 222 patients.