AINeutralarXiv – CS AI · 9h ago5/10
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Switching-time bioprocess control with pulse-width-modulated optogenetics
Researchers propose using pulse-width modulation (PWM) with reinforcement learning to optimize optogenetic bioprocess control, enabling precise gene expression tuning through light-based switching rather than intensity adjustment. This approach addresses the limitation of steep dose-response curves in biotechnology by alternating light ON/OFF states within control periods, improving controllability and production efficiency in protein synthesis and metabolic regulation.