AIBullisharXiv – CS AI · Feb 276/104
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Multi-Dimensional Spectral Geometry of Biological Knowledge in Single-Cell Transformer Representations
Researchers decoded the internal representations of scGPT, a single-cell foundation model, revealing it organizes genes into interpretable biological coordinate systems rather than opaque features. The model encodes cellular organization patterns including protein localization, interaction networks, and regulatory relationships across its transformer layers.