AIBullisharXiv – CS AI · 6h ago7/10
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Anatomically-conditioned Latent Diffusion Model for Data-Efficient Few-Shot Cross-Domain 3D Glioma MRI Synthesis
Researchers propose ALDM, an anatomically-conditioned latent diffusion model that synthesizes 3D brain MRI scans from limited data to improve glioma classification across medical imaging centers. The framework achieves superior synthetic image quality and clinical classification performance with only 16 target images, addressing a critical challenge in medical AI where domain shifts and data scarcity limit model generalization.