AINeutralarXiv – CS AI · 9h ago6/10
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PPI-Net connects molecular protein interactions to functional processes in disease
Researchers introduce PPI-Net, a hierarchical graph neural network that integrates protein-protein interaction networks with biological pathway data to predict cancer outcomes and mechanisms. Demonstrating over 90% balanced accuracy across ten cancer types, the model reveals how molecular changes propagate through biological systems to drive disease, offering both predictive power and mechanistic interpretability.