Multimodal Mixture-of-Experts with Retrieval Augmentation for Protein Active Site Identification

Researchers introduce MERA (Multimodal Mixture-of-Experts with Retrieval Augmentation), a new AI framework for protein active site identification that addresses challenges in drug discovery. The system achieves 90% AUPRC performance on active site prediction through hierarchical multi-expert retrieval and reliability-aware fusion strategies.